[[cardiac_failure]]

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cardiac_failure [2020/05/01 11:57]
Graham Grove [Management]
cardiac_failure [2020/05/01 12:03] (current)
Graham Grove [Management]
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 ** Beta blockers ** ** Beta blockers **
  
-Beta blockers reduce heart rate and thus myocardial energy requirements through blocking the beta-adrenergic receptors. They are associated with mortality improvement as well as improvement of symptoms[(Packer M et al. [[https://​www.ncbi.nlm.nih.gov/​pubmed/​12390947|Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospecive randomized cumulative survival (COPERNICUS) study.]] Circulation 2002)] however they are also frequently associated with adverse effects that also impact on quality of life.+Beta blockers reduce heart rate and thus myocardial energy requirements through blocking the beta-adrenergic receptors. They are associated with mortality improvement as well as improvement of symptoms[(Packer M et al. [[https://​www.ncbi.nlm.nih.gov/​pubmed/​12390947|Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospecive randomized cumulative survival (COPERNICUS) study.]] Circulation 2002)] however they are also frequently associated with adverse effects that also impact on quality of life. Adverse effects include hypotension and bradycardia,​ and worsening of peripheral vascular disease.
  
 ** Ivabradine ** ** Ivabradine **
  • cardiac_failure.txt
  • Last modified: 2020/05/01 12:03
  • by Graham Grove